Mission
Welcome to the web-pages of the Cleveland Center for Structural and Membrane Biology
– the CCSMB. We are a joint venture between Case Western Reserve University (CWRU)
and the Cleveland Clinic Foundation (CCF) and seek to engage structural and membrane
biology interested researchers from the Cleveland area and beyond. A major goal
of CCMSB investigators is to understand the structure and functional interactions
of macromolecular structures, including cellular membranes. These insights will
allow us to design more efficient therapeutics for many human disorders, ranging
from cancer, cardiovascular and neuronal diseases, including blindness, to bacterial
and viral infections. Our mission is to bring together a vibrant research community
and to provide expertise and state of the art facilities in cryo-electron microscopy
(cryo-EM), nuclear magnetic resonance spectroscopy (NMR) and X-ray crystallography.